Targeted Genome Engineering in Human Cells with the Cas9 RNA-guided Endonuclease, image 1 of 11 / 1
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Targeted Genome Engineering in Human Cells with the Cas9 RNA-guided Endonuclease

in Papers i owe my pipettes by Priya Nair

Targeted Genome Engineering in Human Cells with the Cas9 RNA-guided Endonuclease on “Papers i owe my pipettes”, a list by Priya Nair on TheLysts.

Details

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Name
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Field
Genome editing proof-of-concept
What it’s about
Cho et al. using Cas9 RGEN complexes to cut specific sites in human cells and induce indels at respectable frequencies back when this was wild news.
My take
a short paper that reads like a dare: yes, you can just order protein and RNA and start rewriting genomes. dangerous energy for a rainy JP evening.